Fueled by connections

At Agios, building bonds and cultivating relationships are at the heart of our ability to create life-changing therapies for people with rare diseases.

We are a biopharmaceutical company that believes connections unlock potential.

We are a biopharmaceutical company that believes connections unlock potential. We see it in the careers of our people, the evolution of our science, the therapies we are working to bring to market, and the impact we make by working together with patients and collaborators. Each is simply better as a result of the connections we make. By consistently tapping into the knowledge and experience of our patients, partners and colleagues, we elevate our thinking and unearth creative insights that propel ourselves and our science to new levels.

Building on these connections and our leadership in the field of cellular metabolism, we are pioneering therapies for rare diseases, with a near-term focus on developing therapies for hemolytic anemias. Our first rare disease therapy was approved by the FDA for the treatment of hemolytic anemia in adults with pyruvate kinase (PK) deficiency. The lead product candidate in our clinical portfolio, mitapivat, is being evaluated in late-stage clinical trials for thalassemia and sickle cell disease. We are also developing AG-946, a novel PK activator, for the potential treatment of hemolytic anemias and other indications. In addition to these lead programs, we foster a productive research engine and are advancing multiple novel, investigational therapies in preclinical development.

What patients are saying

Teonna Woolford,
living with sickle cell disease

Agios really values patients and advocates — they recognize us as the experts that we are. They listen to our experiences with disease and try to really deeply understand what we deal with everyday as sickle cell warriors. That kind of engagement is a beautiful thing.

Our mission

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to learn more about our mission

How we make a difference

Across our business, and beyond the walls of our organization, we foster connections that drive results and impact for patients.

We share a set of values that promote contribution, engagement and a high regard for others’ points of view.

Find out more about the values that underpin everything we say and everything we do.

Discover Agios Values

Aim High

Come Together

Embrace Differences

Bring Your Whole Self

Blaze New Trails

Our history

The Agios story is rooted in the science of cellular metabolism.

Agios was founded in 2008 to unlock a new field of discovery in cellular metabolism. This singular focus on metabolic disease has taken us from the development of precision therapies in oncology to pioneering new investigational medicines for the treatment of rare diseases. Learn more about our deep history in cellular metabolism and the path we’ve taken since 2008.

See Our Journey

Our leaders

& advisors

We have assembled a world-class roster of leaders, scientific advisors, board directors and staff. We are incredibly proud of our team.

Every person contributes to what makes us special and, importantly, to our ability to bring therapies to market faster and with greater success. Meet the leaders and advisors who are guiding our organization.

Meet Our Leadership Team

Our Commitment to Corporate Social Responsibility

At Agios, we support environmental, social and governance initiatives that are aligned with our values and have the potential to positively impact our patients, employees, communities, and world. In everything we do, we hold ourselves to the highest of ethical standards, and we adhere to strong governance practices that ensure our accountability. This is all to ensure that our work improves the lives of people living with rare diseases and helps make the world a better place.

Discover Our CSR Initiatives

What’s new

at Agios