European Hematology Association Congress 2024
Building connections, pioneering therapies.
Agios Presentations
EHA 2024 Data Room
View our latest news and presentations from the EHA 2024 Hybrid Congress
News
May 11, 2023
Agios to Present Clinical and Translational Data at European Hematology Association Annual Congress
Abstracts
Access All EHA Abstracts
Agios- and Collaborator-Led Presentations
Thalassemia
Data from the global Phase 3 ENERGIZE study of mitapivat in alpha- or beta- non-transfusion-dependent thalassemia.
Plenary Abstracts Session:
Title: ENERGIZE: A Global Phase 3 Study of Mitapivat Demonstrating Efficacy and Safety in Adults with Alpha- or Beta- Non-Transfusion-Dependent Thalassemia
Abstract: S104
Session Date and Time: Saturday, June 15, 14:45-15:15 CEST
Presenter: Ali T. Taher, M.D., Ph.D.; Naef K. Basile Cancer Institute, American University of Beirut Medical Center in Beirut, Lebanon
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Poster Presentations:
Title: Improvements in Fatigue and 6-minute Walk Test in Adults with Alpha- and Beta-Non-Transfusion-Dependent Thalassemia: The Phase 3 ENERGIZE Trial of Mitapivat
Abstract: P1529
Session Date and Time: Friday, June 14, 18-19:00 CEST
Lead Author: Kevin H. M. Kuo, M.D., MSc, FRCPC; Division of Hematology, University of Toronto, Toronto, ON, Canada
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Sickle Cell Disease
A look at the design of the Phase 3 portion of the RISE UP study, as well as information about Phase 2 open-label renal study.
e-Poster Presentations:
Title: Study Design of the Phase 3 Portion of RISE UP: A Phase 2/3, Randomized, Double-blind, Placebo-controlled Study of Mitapivat in Patients with Sickle Cell Disease
Abstract: P2193
Time: Friday, June 14, 9:00 CEST
Lead Author: Biree Andemariam, M.D.; New England Sickle Cell Institute, University of Connecticut Health, Farmington, CT
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Title: The Launch of a Global, Phase 2, Open-label, Multicenter, Single-arm Study of Mitapivat in Patients with Sickle Cell Disease and Nephropathy
Abstract: P2194
Time: Friday, June 14, 9:00 CEST
Lead Author: Fuad El Rassi, M.D.; Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA; Georgia Comprehensive Sickle Cell Center at Grady Health System, Grady Memorial Hospital, Atlanta, GA, USA
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Title: Cost Analysis of Care Expenditures of Patients with Sickle Cell Disease of Hydroxyurea Therapy in a Specialized Blood Center in Rio de Janeiro, Brazil
Abstract: P2306
Time: Friday, June 14, 9:00 CEST
Lead Author: La’Ron Browne, M.D.; Pediatric Hematology Oncology Clinical Fellow, St. Jude Children’s Research Hospital, Memphis, TN
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PK Deficiency
Real-world data describing the characteristics of pediatric patients facing iron overload as part of their disease.
Poster Presentation:
Title: The Characteristics of Pediatric Patients with Pyruvate Kinase Deficiency and Iron Overload
Session Date and Time: Friday, June 14, 18-19:00 CEST
Abstract: P1564
Lead Author: Rachael F. Grace, M.D., MMSc; Dana-Farber/Boston Children’s Cancer and Blood Disorder Center, Harvard Medical School, Boston, MA
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Other Hereditary Hemolytic Anemias
Agios’ collaborators present new preclinical data evaluating mitapivat in other rare hereditary hemolytic anemias.
Oral Presentations:
Title: Ex Vivo Pyruvate Kinase Activation in Hereditary Spherocytosis and Xerocytosis: Improved Enzyme Function and Red Cell Properties
Presentation Time: Sunday, June 16, 11:30-12:45 CEST
Abstract: S299
Presenter: Jonathan R.A. de Wilde, Ph.D. Candidate; Red Blood Cell Research Group, Central Diagnostic Laboratory-Research, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands
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